Effects of artificial gravity during bed rest on bone metabolism in humans
نویسندگان
چکیده
منابع مشابه
Effects of artificial gravity during bed rest on bone metabolism in humans.
We report results from a study designed to explore the utility of artificial gravity (AG) as a countermeasure to bone loss induced by microgravity simulation. After baseline testing, 15 male subjects underwent 21 days of 6 degrees head-down bed rest to simulate the deconditioning associated with spaceflight. Eight of the subjects underwent 1 h of centrifugation (AG; 1 G(z) at the heart, 2.5 G(z...
متن کاملEffects of 21 days of bed rest, with or without artificial gravity, on nutritional status of humans.
Spaceflight and bed rest models of microgravity have profound effects on physiological systems, including the cardiovascular, musculoskeletal, and immune systems. These effects can be exacerbated by suboptimal nutrient status, and therefore it is critical to monitor nutritional status when evaluating countermeasures to mitigate negative effects of spaceflight. As part of a larger study to inves...
متن کاملNitrogen metabolism and bone metabolism markers in healthy adults during 16 weeks of bed rest.
BACKGROUND The associations between nitrogen metabolism and bone turnover during bed rest are still not completely understood. METHODS We measured nitrogen balance (nitrogen intake minus urinary nitrogen excretion) and biochemical metabolic markers of calcium and bone turnover in six males before head-down tilt bed rest (baseline), during 2, 10, and 14 weeks of immobilization, and after reamb...
متن کاملMarkers of bone metabolism during 14 days of bed rest in young and older men
OBJECTIVE We aimed at comparing markers of bone metabolism during unloading in young and older men, and to assess countermeasure effectiveness. METHODS 16 older (60±2 years) and 8 younger men (23±3 years) underwent bed rest (BR) for 14 days. A subgroup of the Older performed cognitive training during BR and supplemented protein and potassium bicarbonate afterwards. Biochemical markers of bone...
متن کاملSex‐specific responses of bone metabolism and renal stone risk during bed rest
The purpose of this study was to directly assess sex differences in bone loss, bone biochemistry, and renal stone risk in bed rest. Bed rest simulates some spaceflight effects on human physiology and can be used to address the potential existence of sex-specific effects on bone metabolism and renal stone risk in space. We combined data from the control subjects in five head-down-tilt bed rest s...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2009
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.91134.2008