Effector T-cell subsets in systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Sex Hormones and Peripheral White Blood Cell Subsets in Systemic Lupus Erythematosus Patients
Background: Systemic Lupus Eyrythematosus (SLE) is an autoimmune disease charac-terized by antibodies to nuclear antigens, particularly anti-dsDNA. Imbalance between production and destruction of immune cells causes cytopenia. Sex hormones have im-munomodulatory effects; estrogen increases the production of autoantibodies in SLE prone NZB/NZW mice. Objective: To investigate the relationship bet...
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Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by increased B cell activity and depressed T cell function. However, the contribution of the immunoregulatory system to its pathogenesis is still unclear. The recent development in the production of monoclonal antibodies and the availability of bench-top flow cytometers have allowed rapid quantitation of peripheral blood ...
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ژورنال
عنوان ژورنال: Current Opinion in Rheumatology
سال: 2011
ISSN: 1040-8711
DOI: 10.1097/bor.0b013e328349a255