Effectiveness of XP-Endo Finisher and passive ultrasonic irrigation on intracanal medicament removal from root canals: a systematic review and meta-analysis

Abstract Background XP-Endo Finisher (XPF) and passive ultrasonic irrigation (PUI) are commonly used in intracanal medicament removal. The effectiveness of these two techniques needs to be compared, evidence-based research should conducted. Methods A comprehensive literature search was conducted PubMed, Web Science, Embase, Cochrane Library, Google Scholar up December 20th, 2020. outcomes the included trials were pooled into Collaboration’s Review Manager 5.3 software. Cochrane’s risk-of-bias tool 2.0 applied assess risk bias. Results Nine articles this systematic review processed for data extraction, eight studies identified meta-analysis. In general, use PUI showed better removal than XPF (odds ratio [OR]: 3.09; 95% confidence interval [CI], 1.96–4.86; P < 0.001). also significantly more efficient apical third (OR: 3.42; CI, 1.32–8.84; = 0.01). For using sodium hypochlorite (NaOCl) alone, effective on medicaments 5.23; 2.79–9.82; However, there no significant difference between when NaOCl ethylenediaminetetraacetic acid (EDTA) combination 1.51; 0.74–3.09; 0.26). addition, whose periods weeks, statistically 7.73; 3.71–16.07; Nevertheless, time one week or over differences found 1.54; 0.74–3.22; 0.25) 1.42; 0.44–4.61; 0.56). Conclusions meta-analysis is first study quantitatively compare With rigorous eligibility criteria, only high-quality randomised controlled trials. indicated that might superior removing from artificial standardized grooves cavities root canal system. anatomical areas, protocol, may influence cleaning efficacy.