Effectiveness of doxylamine-pyridoxine for morning sickness
نویسندگان
چکیده
منابع مشابه
The return to the USA of doxylamine-pyridoxine delayed release combination (Diclegis®) for morning sickness--a new morning for American women.
The US FDA approval in April 2013 of Diclegis®, the doxylamine-pyridoxine combination for morning sickness, is a major milestone, particularly since it is indicated for use in pregnancy and the FDA has labeled it a pregnancy category A drug the strongest evidence of fetal safety. After thirty years of being orphaned from an FDA-labeled drug for the most common medical condition in pregnancy, Am...
متن کاملTreating morning sickness PRN?
QUESTION I received a telephone call from my sister who lives in the United States. She is experiencing moderate symptoms of morning sickness, but she tells me that she was advised to treat her symptoms only pro re nata- meaning, when symptoms re-emerge. Does this make sense? ANSWER No, it does not. Typically, nausea and vomiting of pregnancy continue for weeks and months, and in some cases u...
متن کاملAcupuncture "Clinically Useful" for Morning Sickness
Morning sickness is a condition that occurs naturally during pregnancy. Studies show that between 50-80% of all women experience some nausea or vomiting while pregnant, which usually subsides with time. However, between 1-2% suffer a condition known as hyperemesis gravidarium, an instance of morning sickness so severe and long-lasting that it can cause weight loss, dehydration, and even hospita...
متن کاملOndansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial.
OBJECTIVE To evaluate whether ondansetron or the combination of doxylamine and pyridoxine was superior for the treatment of nausea and vomiting of pregnancy. METHODS This was a double-blind, randomized, controlled trial in which women with nausea and vomiting of pregnancy were assigned to 4 mg of ondansetron plus a placebo tablet or 25 mg pyridoxine plus 12.5 mg of doxylamine for 5 days. The ...
متن کاملDoxylamine-pyridoxine for nausea and vomiting of pregnancy randomized placebo controlled trial: Prespecified analyses and reanalysis
BACKGROUND Doxylamine-pyridoxine is recommended as a first line treatment for nausea and vomiting during pregnancy and it is commonly prescribed. We re-analysed the findings of a previously reported superiority trial of doxylamine-pyridoxine for the treatment of nausea and vomiting during pregnancy using the clinical study report obtained from Health Canada. METHODS AND FINDINGS We re-analyse...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2016
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2016.01.186