EFFECTIVE CONTROL OF ATRIAL FIBRILLATION CAN BE ACHIEVED WITH VERY LOW DOSES OF AMIODARONE

Very low fluoroscopy ablation for atrial fibrillation can be fast and safe.

Amiodarone for atrial fibrillation.

n engl j med 356;9 www.nejm.org march 1, 2007 935 This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presen...

Can Cancer Be Treated with Low Doses of Radiation ?

Historical Background ABSTRACT Strong sources of radiation became available in the 1950s. Since then, intense ionizing beams have been employed against cancer to destroy or shrink tumors. Today, nearly all radiation treatments for cancer apply high doses to local regions of the body. It is generally believed that radiation in any amount will only damage cells and that the mutated cells could be...

Ablation of Atrial Fibrillation: How Can Less Be More?

Real-time assessment of pulmonary vein disconnection during cryoablation of atrial fibrillation: can it be 'achieved' in almost all cases?

AIM Real-time assessment of pulmonary vein (PV) disconnection is possible using an inner circular mapping catheter during cryoablation of atrial fibrillation (AF). However, it has been recently demonstrated that such continuous monitoring may only be possible in <50% of PVs. We hypothesized that a stepwise mapping approach, including pacing manoeuvres, could optimize monitoring of real-time PV ...