Effect of Spp1 on nerve degeneration and regeneration after rat sciatic nerve injury
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منابع مشابه
P187: Dose-Dependent Delay of Wallerian Degeneration Induced by Dexamethasone after Sciatic Nerve Transection in Rat
Wallerian degeneration is an innate immune response which occurs after some kinds of nerve damages such as neurodegenerative disease and acute axonal injury. In clinic, dexamethasone as an anti-inflammatory drug has been used for many years to treat nerve injuries. In present study, we aimed to study the effects of various doses of dexamethasone on the Wallerian degeneration in rat. Twentyseven ...
متن کاملP49: The Evaluation of Aqueous Extract of Glycyrrhiza Glabra on Nerve Recovery in the Rat after Sciatic Nerve Injury
Peripheral nerve injury requires a long recovery period, and recovery, once attained, usually is incomplete. Inflammatory procedures may inhibit functional recovery after nerve injury and produce cell death in both the central nervous system and the peripheral nervous system. Since the glycyrrhiza glabra extract has anti-inflammatory effects, it could reduce the severity of injury. The aim of t...
متن کاملAge-Dependent Regeneration by Using Electromyographical Study Foliowing Sciatic Nerve Injury in Rat
Purpose: There are extensive evidences that show axonal processes of the nervous system (peripheral and/or central) may be degenerated after nerve injuries. Axonal regeneration is relation to various factors. In this investigation we decided to evaluate the effects of nerve regeneration age-dependent on injured rat sciatic nerv. Materials and Methods: For this study, the right sciatic nerve of...
متن کاملEffect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model
BACKGROUND Zofenopril is an antioxidant agent which has been shown to have beneficial effects in hypertension and heart failure. The aim of this study was to test the effects of Zofenopril on nerve regeneration and scarring in a rat model of peripheral nerve crush injury. METHODS Twenty-one adult Sprague-Dawley rats underwent a surgical procedure involving right sciatic nerve crush injury. 15...
متن کاملLocalization of Epidermal-Type Fatty Acid Binding Protein (E-FABP) in Degeneration and Regeneration of Sciatic Nerve after Crush Injury in Mouse
Purpose:The regeneration of axon and myelin sheet after crush injury of peripheral nerves involves interaction of several types of cells, including Schwann cells, monocyte, macrophage and fibroblast. Among them, haematogenous macrophages invading into the peripheral nervous systein play a major role in myelin uptake during Wallerian degeneration. Materials and Methods: In this study 35 C57/BL6 ...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2017
ISSN: 1471-2202
DOI: 10.1186/s12868-017-0348-1