Effect of β-sitosterol self-microemulsion and β-sitosterol ester with linoleic acid on lipid-lowering in hyperlipidemic mice

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Preparation , Analysis and Cholesterol Lowering Effect of a Novel Microcrystalline β - sitosterol Suspension in Oil

Christiansen, L.I, 2002. Preparation, analysis and cholesterol lowering effect of a novel microcrystalline β-sitosterol suspension in oil and phase behaviour of β-sitosterol with cholesterol. Dissertationes Biocentri Viikki Universitatis Helsingiensis 11/2002, pp. 54 ISBN 952-10-0508-4 (print) ISBN 952-10-0509-2 (pdf) ISSN 1239-9469 Few efforts have been made to formulate preparations suitable ...

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β-sitosterol interacts with pneumolysin to prevent Streptococcus pneumoniae infection

Pneumolysin is one of the major virulence factors elaborated by Streptococcus pneumoniae; this toxin is a member of the cholesterol-dependent cytolysins. Engagement of cholesterol induces the formation of a multi-subunit complex by pneumolysin that lyses host cells by forming pores on the membrane. Because pneumolysin released by bacteria which have been killed by conventional antibiotics is st...

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Synthesis and Solubility of Hydrophilic Derivatives of β- Sitosterol

In this study, hydrophilic derivatives of β-sitosterol, which is known to have potential to reduce blood cholesterol levels, were synthesized by the esterification of poly(ethylene glycol) (PEG) and β -sitosterol with carboxylic functionality in the presence of dehydrating agents and a basic catalyst. By adjusting the molar ratios of reactants in the esterification reaction, hydrophilic β-sitos...

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A concise synthesis of β-sitosterol and other phytosterols

A convenient synthesis of sidechain-modified phytosterols is achieved via a temporary masking of the stigmasterol 5,6-alkene as an epoxide. Following performance of the desired modification, the alkene is regenerated through a mild deoxygenation. The approach is applied to the syntheses of β-sitosterol and campesterol acetate, and suggests a facile route to the (Z)-isomers of Δ22–23

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ژورنال

عنوان ژورنال: Lipids in Health and Disease

سال: 2019

ISSN: 1476-511X

DOI: 10.1186/s12944-019-1096-2