Effect of Preexisting Immunity to Tetanus Toxoid on the Efficacy of Tetanus Toxoid-Conjugated Heroin Vaccine in Mice
نویسندگان
چکیده
منابع مشابه
Severe tetanus--in spite of tetanus toxoid.
A 66-year-old man sustained an injury to his right foot while gardening. Despite receiving tetanus toxoid one hour later and adequate wound toilet, he developed severe tetanus complicated with autonomic dysfunction six days later. He died 20 days after admission. This case shows that tetanus toxoid alone may not be sufficient to prevent tetanus in wounded patients. Careful consideration must be...
متن کاملImmunological studies on tetanus toxoid
T toxoid is one of the most successful vaccines used in immunization programme almost all over the world. Neonatal tetanus can be prevented by immunizing women of childbearing age with tetanus toxoid, either during pregnancy or outside of pregnancy. Tetanus vaccine is used either in mono or in combination with other antigens i.e. Diphtheria, Pertussis (whole cell or acellular), Hepatitis B, Hae...
متن کاملImmunization with Tetanus Toxoid
Although immunization with tetanus toxoid cannot be expected to produce an adequate permanent immunity, a number of investigators have confirmed and extended the observation of Ramon3 to the effect that an organism, once immunized, will respond to further injections of toxoid with an accelerated and increased antitoxin production. That this response to the "injection de rappel" does occur has b...
متن کاملStudies on Tetanus Toxoid: III. Antitoxic Response in Guinea Pigs Immunized with Tetanus Alum-precipitated Toxoid Followed by Tetanus Spores.
When an individual has been given one or more injections of tetanus toxoid and, at a later date, is injured and possibly infected with Clostridium tetani, what further precautions should be taken: (1) Administer antitoxin? (2) Give another injection of tetanus toxoid to accelerate the production of antitoxin? (3) Give no further treatment, depending on his present immunity to take care of the i...
متن کاملTetanus toxoid immunization to reduce mortality from neonatal tetanus
BACKGROUND Neonatal tetanus remains an important and preventable cause of neonatal mortality globally. Large reductions in neonatal tetanus deaths have been reported following major increases in the coverage of tetanus toxoid immunization, yet the level of evidence for the mortality effect of tetanus toxoid immunization is surprisingly weak with only two trials considered in a Cochrane review. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vaccines
سال: 2021
ISSN: 2076-393X
DOI: 10.3390/vaccines9060573