Effect of Non-surgical Periodontal Therapy on Salivary Melatonin Levels

Objective: Melatonin, a hormone secreted predominantly by pineal gland in circadian manner, has antioxidant and anti-inflammatory effects. The current research is conducted to explore the influence of non-surgical periodontal therapy (NSPT) on levels salivary melatonin subjects with gingivitis periodontitis. Methods: Sixty systemically healthy participants were included this study; groups are as follows: (G), chronic periodontitis (CP), generalized aggressive (GAP) periodontally (H). NSPT was applied G group patients for 2 sessions, CP GAP 4 sessions. Plaque gingival indices, probing depth (PD), bleeding (BOP), clinical attachment level (CAL) documented at baseline 3 months post – treatment early morning samples collected. ELISA used detect saliva. Pittsburgh Sleep Quality Index (PSQI) questionnaire performed evaluate sleep quality patients. Results: At baseline, significant difference index, PD, BOP CAL values detected among all (p