Effect of N-acetylcysteine on Hepatic Ischemiareperfusion Injury in Normal and Steatotic Rats
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولEffect of combination therapy with pramipexole and n-acetylcysteine on global cerebral ischemic reperfusion injury in rats
Objective(s): The study was intended to investigate the combined influence of two neuroprotective agents pramipexole and n-acetylcysteine on global cerebral ischemic reperfusion injury (GCIRI) model in rats.Materials and Methods: GCIRI was induced by bilateral common carotid artery ligation (BCCA) in rats. Animals were divided into six groups. Groups I, II, and III received saline intraperitone...
متن کاملProtective effect of N-acetylcysteine in isoniazid induced hepatic injury in growing rats.
Status of oxidative/antioxidative profile was the mechanistic approach to inumerate the nature of protection by N-acetylcysteine (NAC) in isoniazid (INH) exposed experimental animals. Analysis of lipid peroxidation, thiol levels, cytochrome P450, superoxide dismutase (SOD), catalase, glutathione peroxidase, reductase and transferase were estimated in liver along with the body and liver weight o...
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15 صفحه اولS-Nitroso-N-Acetylcysteine Ameliorates Ischemia-Reperfusion Injury In The Steatotic Liver
BACKGROUND Steatosis is currently the most common chronic liver disease and it can aggravate ischemia-reperfusion (IR) lesions. We hypothesized that S-nitroso-N-acetylcysteine (SNAC), an NO donor component, can ameliorate cell damage from IR injury. In this paper, we report the effect of SNAC on liver IR in rats with normal livers compared to those with steatotic livers. METHODS Thirty-four r...
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ژورنال
عنوان ژورنال: Bulletin of Egyptian Society for Physiological Sciences
سال: 2011
ISSN: 2356-9514
DOI: 10.21608/besps.2011.36086