Effect of methonolic extract of Vitex negundo on haloperidol induced catalepsy in albino mice

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Effect of ethanolic leaf extract of Ocimum sanctum on haloperidol-induced catalepsy in albino mice

Neuroleptic drugs used in the treatment of schizophrenia and other affective disorders are known to produce extrapyramidal side effects. Catalepsy induced by these drugs in Department of Pharmacology, Kasturba Medical College, animals has been used as a model for the extrapyramidal side effects associated with Mangalore 575 001, Karnataka, antipsychotic agents in human beings. In the present st...

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Effect of NR-ANX-C (a polyherbal formulation) on haloperidol induced catalepsy in albino mice.

BACKGROUND & OBJECTIVE Use of typical antipsychotics like haloperidol in treatment of schizophrenia is associated with a high incidence of extrapyramidal side effects. In rodents, administration of haloperidol leads to the development of a behavioural state called catalepsy, in which the animal is not able to correct an externally imposed posture. In the present study we evaluated the anticatal...

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Effect of Tribulus terrestris on Haloperidol-induced Catalepsy in Mice

Haloperidol, an antipsychotic drug, leads to the development of a behavioural state called catalepsy, in which the animal is not able to correct an externally imposed posture. In the present study we have attempted to evaluate the anticataleptic effect of Tribulus terrestris on haloperidol-induced catalepsy in albino mice. Mice were allocated to four groups, each group containing six animals. B...

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EFFECT OF ETHANOLIC EXTRACT OF LEAVES OF Vitex negundo L. ON ACETIC ACID INDUCED COLITIS IN ALBINO RATS

ObjectiveAs the leaves of Vitex negundo L. possess anti-inflammatory and antioxidant properties, this study has been undertaken to evaluate the effect of Vitex negundo L. in experimentally induced inflammatory bowel disease (IBD) and to find its probable mechanism of action including its antioxidant potential. Methods-The extract of Vitex negundo L. was prepared by percolation method. Acute tox...

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ژورنال

عنوان ژورنال: International Journal of Basic & Clinical Pharmacology

سال: 2020

ISSN: 2279-0780,2319-2003

DOI: 10.18203/2319-2003.ijbcp20201188