Effect of intrathecal oxcarbazepine on rat tail flick test-determined morphine tolerance

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of intrathecal oxcarbazepine on rat tail flick test-determined morphine tolerance

337 Received: January 4, 2009. Revised: 1st, January 14, 2009; 2nd, January 29, 2009. Accepted: May 22, 2009. Corresponding author: Jong-Yeon Park, M.D., Department of Anesthesiology and Pain Medicine, ASAN Medical Center, University of Ulsan, College of Medicine, 388-1, Pungnap-dong, Songpa-gu, Seoul 138-736, Korea. Tel: 82-2-3010-3867, Fax: 82-2-470-1363, E-mail: [email protected] Co...

متن کامل

The effects of intrathecal gabapentin on spinal morphine tolerance in the rat tail-flick and paw pressure tests.

Analgesic tolerance to opioids has been described in both experimental and clinical conditions and may limit the clinical utility of these drugs. We have previously shown that systemic gabapentin (GBP), a non-opioid drug, prevents and reverses tolerance to systemic morphine in the rat. In this study, we investigated the effect of intrathecal GBP on spinal morphine tolerance. Studied rats were g...

متن کامل

Nimodipine is more effective than nifedipine in attenuating morphine tolerance on chronic co-administration in the rat tail-flick test.

Opioids, when co-administered with L-type calcium channel blockers (L-CCBs) show morphine like higher antinociceptive effect. This antinociceptive effect has been further investigated using a different experimental paradigm. The effect of two different L-CCBs (nifedipine and nimodipine) on morphine-induced antinociception was studied by the tail-flick test (40 min after morphine administration)...

متن کامل

The central nucleus of the amygdala contributes to the production of morphine antinociception in the rat tail-flick test.

Current models of endogenous pain control circuitry emphasize neural substrates within the brainstem and spinal cord. We have recently shown, however, that the central nucleus of the amygdala (Ce) contributes to morphine-induced suppression of formalin-induced nociceptive behaviors. In the four experiments reported here, we investigated the possibility that the Ce also contributes to morphine-i...

متن کامل

Evaluation of the analgesic effect of Mellissa officinalis extract by tail-flick test in mice

  Bibliographical studies have been done on plants that are used as analgesics in traditional medicine, and Mellissa officinalis or Lemon Balm (LB) that there are some evidence indicating for its application as analgesics or its probable analgesic effect was selected for evaluation of analgesic effect by tail-flick test in mice. After scientific identification, the leaves and flowered branches ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Korean Journal of Anesthesiology

سال: 2009

ISSN: 2005-6419,2005-7563

DOI: 10.4097/kjae.2009.57.3.337