Effect of Giving Jackfruit (Artocarpus heterophyllus) Leaves Crude Extract as An Alternative Antibacterial of Edwardsiella tarda Bacteria In Vitro

Barriers to cultivation activities are disease attacks, one of which is caused by infection with the bacterium Edwardsiella tarda. Treatment efforts can be made using natural ingredients such as jackfruit (A. heterophyllus) leaves. This study aims determine content antibacterial compounds in leaves crude extract and their effect on tarda bacteria vitro. The inhibition test used disc five different concentrations three replications: 75 mg/L, 150 225 300 mg/L 375 a comparison two types controls (positive 5 chloramphenicol antibiotics negative no treatment) Tryptone Soy Agar (TSA) media incubated for 2x24 hours. results phytochemical screening proved that contains flavonoids, alkaloids, tannins saponins. E dose gave highest 7.80 mm treatment A lowest 4.38 mm. relationship between given parameter form resulting inhibitory power obtained equation y = 0.0111x + 3.6297 an R2 value 0.974 means 97% affects E.