Effect of Cytokines on Anticryptococcal Activity of Human Microglial Cells
نویسندگان
چکیده
منابع مشابه
Effect of cytokines on anticryptococcal activity of human microglial cells.
The effect of selected cytokines on the antifungal activity of human microglia was studied with encapsulated and acapsular strains of Cryptococcus neoformans. None of the cytokines tested increased the fungistatic activity of microglia, suggesting that killing of cryptococci within the central nervous system is dependent on other host defense mechanisms.
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The anticryptococcal activity of peripheral blood polymorphonuclear leukocytes (PMN) and monocytes was compared on plastic versus human umbilical vein endothelial cell surfaces. Various amounts of PMN and monocytes were incubated on plastic or endothelial surfaces and then challenged for 18 h with Cryptococcus neoformans. Both phagocyte populations exhibited significantly more anticryptococcal ...
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ژورنال
عنوان ژورنال: Clinical Diagnostic Laboratory Immunology
سال: 1998
ISSN: 1071-412X,1098-6588
DOI: 10.1128/cdli.5.3.410-411.1998