Effect of Cimetidine on Semen Parameters, FSH and LH in Male Rats

Cimetidine is effective drugs on male reproductive system by its effect semen characteristic or parameters such as sperm motility, morphology and count, also cimetidine sexual hormones, were testosterone, FSH LH. In this investigation, 20 rats randomly classified into two groups, Control group(G1): This group contain 10 receiving normal saline group( G2): 100mg/kg. B.W. from group, during the period 38days from(20. Novmber.2022 to 28. Desmber.2022), after end study animals slaughtered, then, seminal samples taken epididymis, well blood samples, converted serum for purpose of work hormonal analysis. Group treated with showed significantly decrease in motility increase immotile abnormal normal, counts. Also level testosterone FSH, but LH, it can be concluded that exerted a significant harmful effects characteristics hormones.