Effect of botulinum toxin a and nitroglycerin on random skin flap survival in rats
نویسندگان
چکیده
منابع مشابه
Effect of botulinum toxin A and nitroglycerin on random skin flap survival in rats.
BACKGROUND A suitable pharmacological substitute for the well-established surgical delay technique for random skin flaps to increase viability has been elusive. OBJECTIVE To evaluate the effects of nitroglycerin and botulinum toxin type A on random flap survival in a rat model. METHODS The present controlled experimental study was performed in the four groups of rats. One week after interve...
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Introduction: In this study, the effect of botulinum toxin A and clopidogrel and concomitant administration of them in the survival of random skin flap in rat model were studied. Correspondence: Ghasemali. Khorasani, MD. Surgery Department, Immam Khomeini Hospital Complex, Tehran University of Medical Sciences. ...
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BACKGROUND Necrosis of skin flaps is considered as an important complication in reconstructive surgery. We conducted an experimental study to investigate the efficacy of low-molecular weight heparin, clopidogrel and their combination to improve the flap survival. METHODS Forty male, adult Sprague-Dawlay rats were divided randomly into 4 groups. Standard rectangular, distally based dorsal ran...
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Objective(s): Skin flap necrosis is the most common postoperative side effect in reconstructive surgeries. Glutamine (GLN) has been shown to accelerate wound healing process. The purpose of this study was to evaluate the effects of GLN either in free form or in the dipeptide form along with L- alanyl (Ala-GLN) on random skin flaps survival in rats.Materials and Methods: Dorsal skin flaps with c...
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ژورنال
عنوان ژورنال: Plastic Surgery
سال: 2016
ISSN: 2292-5503,2292-5511
DOI: 10.1177/229255031602400208