Effect of addition of intrathecal preservative free magnesium sulfate with 0.5% bupivacaine heavy and fentanyl with 0.5% bupivacaine heavy on post-operative pain relief in patients undergoing hysterectomy

Background: Spinal anesthesia is the most common neuraxial for infraumblical surgeries. The use of various adjuvants has become popular in today’s scenario to enhance its quality. Aims and Objectives: aim this study was evaluate onset, duration sensory motor block, hemodynamic effects (if any), post-operative analgesia, adverse fentanyl or magnesium given intrathecally with 0.5% bupivacaine heavy patients undergoing hysterectomy. Materials Methods: This prospective randomized double-blinded conducted total sixty hysterectomy, divided into two groups 30 each. Group F received 25 μg 3 mL M 100 mg sulfate heavy. onset blockade, hemodyamics, side were assessed. Results: mean time block less (P<0.001). Duration sensory, analgesia more group (P<0.001), whereas incidence such as bradycardia, hypotension, shivering magnesium. Conclusion: Our concluded that addition adjuvant effectively augmented quality spinal anesthesia, but provided stable hemodynamics lesser compared fentanyl.