Effect of 3-Nitro (3-Nitro-4-Hydroxyphenyl-arsonic acid 5% premix) on adult of rosy barb

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Angiogenic Potential of 3-Nitro-4-Hydroxy Benzene Arsonic Acid (Roxarsone)

BACKGROUND Roxarsone (3-nitro-4-hydroxy benzene arsonic acid) is an arsenic compound widely used in the poultry industry as a feed additive to prevent coccidiosis, stimulate growth, and to improve tissue pigmentation. Little is known about the potential human health effects from roxarsone released into the environment from chicken waste or from residual compound in chicken products. OBJECTIVE...

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In the title compound, C(10)H(11)N(3)O(2), the nitro group is essentially coplanar with the aromatic ring [dihedral angle = 1.3 (3)°] and forms an intra-molecular amine-nitro N-H⋯O hydrogen bond. In the crystal, weak inter-molecular aromatic C-H⋯O(nitro) hydrogen bonds link the mol-ecules. Weak aromatic ring π-π inter-actions [minimum ring centroid separation = 3.7744 (13) Å] are also present.

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Biotransformation of 3-nitro-4-hydroxybenzene arsonic acid (roxarsone) and release of inorganic arsenic by Clostridium species.

The extensive use of 3-nitro-4-hydroxybenzene arsonic acid (roxarsone) in the production of broiler chickens can lead to increased soil arsenic concentration and arsenic contaminated dust. While roxarsone is the dominant arsenic species in fresh litter, inorganic As (V) predominates in composted litter. Microbial activity has been implicated as the cause, but neither the specific processes nor ...

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Five times the recommended dose of 3-nitro-4-hydroxyphenylarsonic acid (187.5 mg kg-1) induces a pathognomonic clinical syndrome in pigs. The main clinical features are not continually present but are inducible only by exercise. From day 11 on the experimental diet a nervous syndrome was inducible. This manifested as muscle tremors and clonic convulsive episodes. Paraparesis developed by day 22...

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ژورنال

عنوان ژورنال: THE ASIAN JOURNAL OF ANIMAL SCIENCE

سال: 2016

ISSN: 0973-4791,0976-8963

DOI: 10.15740/has/tajas/11.1/9-12