Efektivitas Anti-Ulcer Fukoidan Dari Rumput Laut Coklat Sargassum Polycystum
نویسندگان
چکیده
Tujuan penelitian untuk mengetahui efek antiulkus isolat fukoidan dan Sargassum polycystum terhadap tikus putih jantan. Sampel terdiri dari 45 ekor jantan dibagi 9 kelompok yaitu normal, CMC-Na, sukralfat, 25mg/kgbb, 50mg/kgbb 100mg/kgbb. Perlakuan diberi per oral selama 10 hari. Pada hari ke-10, dipuasakan 24 jam diberikan induksi etanol P.A. Kemudian dikorbankan diambil lambung dilakukan pemeriksaan makroskopik mikroskop. Hasil karakteristik simplisia diperoleh kadar air 9,05%, susut pengeringan 8,74% rendemen hasil isolasi adalah 4,01% 6,4%. identifikasi secara spektrofotometri FTIR menunjukkan bentuk spektrum kurva serapan identik dengan baku pembanding fukoidan. Persentase jumlah tukak masing-masing dosis yaitu, 25mg/kgbb (1.04 0,85), (0,84 0,67), 100mg/kgbb (0,21 0,40). Kesimpulan memiliki gastroprotektif optimum
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ژورنال
عنوان ژورنال: Jurnal Syntax Admiration
سال: 2021
ISSN: ['2722-7782', '2722-5356']
DOI: https://doi.org/10.46799/jhs.v2i2.111