Efektifitas Ekstrak Daun Bidara Laut (Ziziphus mauritiana) terhadap Penyembuhan Luka Bakar pada Tikus Putih (Rattus norvegicus L.) Galur Wistar

نویسندگان

چکیده

Luka bakar adalah kerusakan kulit yang disebabkan oleh trauma panas atau dingin (frost bite) . Penyebabnya api, air panas, listrik, bahan kimia, radiasi, dan Trauma Penyembuhan luka melalui tiga fase, yaitu fase inflamasi, proliferasi, remodeling. Bidara laut (Ziziphus mauritiana) mengandung senyawa alkaloid, glikosida, saponin, flavonoid, terpenoid, fenolat berkhasiat sebagai antioksidan, anti antimikroba, antijamur mencegah tumor. Tujuan penelitian ini membandingkan efektivitas ekstrak daun bidara kelompok pengobatan lainnya pada penyembuhan bakar. Metode true experimental dengan rancangan post-test control group design menggunakan observasi skor Nagaoka. Analisis data uji Man-Whitney. Hasil didapatkan rata-rata Nagaoka antara perlakuan kontrol mengenai alergi 3:3, infeksi waktu 1,8:1,4. Sedangkan Skor total untuk 7,88 7,44. Uji Mann Whitney menunjukkan perbedaan signifikan nilai 0,010 (p<0,05). Ekstrak efektif dalam tikus putih (Rattus norvegicus L) galur wistar.

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ژورنال

عنوان ژورنال: Jurnal Implementa Husada

سال: 2023

ISSN: ['2722-0877']

DOI: https://doi.org/10.30596/jih.v4i3.15856