Educational lecture on colony stimulating factor(Granulopoietin).

STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR

In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both...

Educational Lecture

― ― S30 ― US FDA is a regulatory body to regulate not only drugs but also medical devices, biological products, cell therapy products, cosmetics and food additives. The largest laboratory animal users are laboratories that follow the government requirement for safety testing and the amendment of GLP regulation is interested in by laboratory animal industry. In USA, GLP is regulated by law inste...

Colony-stimulating Factor-1, and Recombinant Murine Granulocyte-Macrophage Colony-stimulating Factor on Myelopoiesis in Mice

Purified murine colony-stimulating factors (CSF) recombinant interleukin 3 (IL-3), natural CSF-1, and recombinant granulocyte-macrophage (GM) CSF were assessed in vivo for their effects on BDF, mouse bone marrow and spleen granulocyte-macrophage (CFU-GM), erythroid (BFU-E), and multipotential (CFU-GEMM) progenitor cells in untreated mice and in mice pretreated with purified iron-saturated human...

Granulocyte colony-stimulating factor.

In the background section of their abstract, Woei-Cherng Shyu and associates state that because granulocyte colony-stimulating factor (G-CSF) has anti-inflammatory and neuroprotective properties and the capacity to mobilize stem cells, it has the potential to be used in treatment of stroke. However, there are limited data about the effects of G-CSF on hemostasis. It has been suggested that G-CS...

Macrophage Colony-Stimulating Factor