Editorial: The Complexity of Primary Antibody Deficiencies
نویسندگان
چکیده
EDITORIAL article Front. Immunol., 21 April 2021 | https://doi.org/10.3389/fimmu.2021.635482
منابع مشابه
Autoimmunity in Primary Antibody Deficiencies.
Primary antibody deficiencies (PADs) are the most common inherited primary immunodeficiencies in humans, characterized by hypogammaglobulinemia, an inability to produce specific antibodies, and recurrent infections mainly caused by encapsulated bacteria. However, it has been shown that inflammatory disorders, granulomatous lesions, lymphoproliferative diseases, cancer, and autoimmunity are asso...
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Background: Primary antibody deficiency, the most common primary immunodeficiency disorder, represents a heterogeneous spectrum of conditions caused by a defect in any critical stage of B cell development and is characterized by impaired production of normal amounts of antigen-specific antibodies. Objective: This retrospective study aimed at description and analysis of demographic, clinical, im...
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common variable immunodeficiency (cvid) and selective iga deficiency (sigad) are the most common primary antibody deficiencies. these two diseases may have coincidence in one family and sigad can progress to cvid which suggest common underlying genetic defects between sigad and cvid. this study was designed to find the prevalence of multiple cases in families of iranian patients with cvid or si...
متن کاملImpact of delayed diagnosis in children with primary antibody deficiencies.
BACKGROUND Primary antibody deficiencies (PADs) are heterogeneous group of disorders, characterized by hypogammaglobulinemia and increased susceptibility to recurrent infections. To evaluate the diagnostic delay in Iranian PADs in association with their infections, we scored such manifestations to find an association between such delay and the scoring system. METHODS Forty-eight patients with...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2021
ISSN: ['1664-3224']
DOI: https://doi.org/10.3389/fimmu.2021.635482