منابع مشابه
Editorial: Natriuretic Hormones
The link between renal sodium excretion and body fluid volumes has been a topic of interest since the early days of renal physiology (1). Glomerular filtration rate (GFR) and aldosterone were the first two controllers of renal sodium excretion to be recognized. A “third factor” was discovered when de Wardener and colleagues showed that volume expansion natriuresis still occurred in dogs given s...
متن کاملNatriuretic Hormones in Brain Function
Natriuretic hormones (NH) include three groups of compounds: the natriuretic peptides (ANP, BNP and CNP), the gastrointestinal peptides (guanylin and uroguanylin), and endogenous cardiac steroids. These substances induce the kidney to excrete sodium and therefore participate in the regulation of sodium and water homeostasis, blood volume, and blood pressure (BP). In addition to their peripheral...
متن کاملIdentification of Putative Natriuretic Hormones Isolated from Human Urine
This brief review describes some representative methodological approaches to the isolation of putative endogenous inhibitors of epithelial sodium transport - i.e., as ouabain-like factors (OLF) that inhibit the sodium transport enzyme Na-K-ATPase or inhibit the epithelial sodium channel (ENaC). Gel chromatography and reverse-phase (RP)-high performance liquid chromatography (HPLC) of lyophilize...
متن کاملNatriuretic Hormones, Endogenous Ouabain, and Related Sodium Transport Inhibitors
The work of deWardener and colleagues stimulated longstanding interest in natriuretic hormones (NHs). In addition to the atrial peptides (APs), the circulation contains unidentified physiologically relevant NHs. One NH is controlled by the central nervous system (CNS) and likely secreted by the pituitary. Its circulating activity is modulated by salt intake and the prevailing sodium concentrati...
متن کاملEditorial Is atrial natriuretic peptide really a hormone ?
Since the 1950s when granules were first observed histologically within the atrial wall there has been intense interest in their function. Two early key papers were those of Marie et al' and de Bold,2 who showed that the granulation was related to the water/electrolyte balance, although a first time reader's starting point should be the meticulous histological investigation of Jamieson and Pala...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2015
ISSN: 1664-2392
DOI: 10.3389/fendo.2015.00108