Editorial: Function of Renal Sympathetic Nerves
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چکیده
منابع مشابه
Editorial: Function of Renal Sympathetic Nerves
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide. The incidence of CVD is increasing in association with the growing prevalence of hypertension, diabetes, and obesity. This is occurring despite established effective therapies for hypertension. Thus, new methods for risk reduction are still needed (Cutler et al., 2008). The aim of this research topic was to ...
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Heart failure (HF) is a serious debilitating condition with poor survival rates and an increasing level of prevalence. HF is associated with an increase in renal norepinephrine (NE) spillover, which is an independent predictor of mortality in HF patients. The excessive sympatho-excitation that is a hallmark of HF has long-term effects that contribute to disease progression. An increase in direc...
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Other than efferent sympathetic innervation, the kidney has peptidergic afferent fibers expressing TRPV1 receptors and releasing substance P. We tested the hypothesis that stimulation of afferent renal nerve activity with the TRPV1 agonist capsaicin inhibits efferent renal sympathetic nerve activity tonically by a neurokinin 1 receptor-dependant mechanism. Anesthetized Sprague-Dawley rats were ...
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Renal Sympathetic Denervation: Renal Function Concerns To the Editor: We have read the report of the Simplicity HTN-1 investigators on the 2-year durability of blood pressure reduction induced by catheter-based renal sympathetic denervation with great excitement1 because it represents a promising approach for treatment of resistant hypertension.2 However, several concerns arise that require cla...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2017
ISSN: 1664-042X
DOI: 10.3389/fphys.2017.00642