منابع مشابه
Editorial: Cell Fate
The complexity and plasticity of cell fate determination has intrigued cell and developmental biologists for decades. Cellular differentiation is the acquisition of specialized characteristics; which is intimately associated with changes in gene expression, alterations of chromatin, and changes in nuclear architecture. Differentiating tissues exhibit a progressive restriction of cellular plasti...
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Although the mechanisms and control of cellular reproduction have been studied for many years, it seems clear that the year under review has been one of the most remarkable yet in terms of the breadth and depth of the insights it has brought us. It also seems clear that this is no accident, and that we can expect more remarkable years of discovery in the near future. The reason is, of course, t...
متن کاملHermaphrodite cell-fate specification.
There are two sexes in C. elegans, hermaphrodite and male. While there are many sex-specific differences between males and hermaphrodites that affect most tissues, the basic body plan and many of its structures are identical. However, most structures required for mating or reproduction are sexually dimorphic and are generated by sex-specific cell lineages. Thus to understand cell fate specifica...
متن کاملStochasticity and cell fate.
Fundamental to living cells is the capacity to differentiate into subtypes with specialized attributes. Understanding the way cells acquire their fates is a major challenge in developmental biology. How cells adopt a particular fate is usually thought of as being deterministic, and in the large majority of cases it is. That is, cells acquire their fate by virtue of their lineage or their proxim...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2016
ISSN: 1664-8021
DOI: 10.3389/fgene.2015.00363