منابع مشابه
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Saquinavir (SQV) is a protease inhibitor widely used for the treatment of human immunodeficiency virus (HIV) infection. We profiled SQV metabolism in mice using a metabolomic approach. Thirty SQV metabolites were identified in mouse feces and urine, of which 20 are novel. Most metabolites observed in mice were recapitulated in human liver microsomes. Among these novel metabolites, one a-hydroxy...
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The effect of rifampicin on the pharmacokinetics of fexofenadine enantiomers was examined in healthy subjects who received fexofenadine alone or with single or multiple doses of rifampicin (600 mg). A single coadministered dose of rifampicin significantly decreased the oral clearance (CLtot/F) and renal clearance (CLr) of Sand R-fexofenadine by 76 and 62%, and 73 and 62%, respectively. Even aft...
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Since qualifying as an anaesthetist in Johannesburg, Jeffrey Lipman has been working full-time in Intensive Care Units since1979. Prior to moving to Brisbane in 1997, he was Head of Intensive Care at Baragwanath Hospital, where his interest in tetanus originated. He has published over 100 articles in peer-reviewed journals on a wide variety of topics. His research interests most recently have b...
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RNA helicases are molecular motors that are involved in virtually all aspects of RNA metabolism. Eukaryotic initiation factor (eIF) 4A is the prototypical member of the DEAD-box family of RNA helicases. It is thought to use energy from ATP hydrolysis to unwind mRNA structure and, in conjunction with other translation factors, it prepares mRNA templates for ribosome recruitment during translatio...
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Th is study provides a timely update of some empirical fi ndings of ecotourism experience in relation to Chinese tourists’ post-trip behaviors. Based on a qualitative research approach through in-depth interview with 28 Chinese domestic tourists, the authors show that Chinese tourists explicitly or implicitly have adapted environmentally friendly lifestyles after their ecotourism travel, althou...
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ژورنال
عنوان ژورنال: Australasian Journal of Educational Technology
سال: 2005
ISSN: 1449-5554,1449-3098
DOI: 10.14742/ajet.1320