Ectothermic telomeres: it's time they came in from the cold

Ectothermic telomeres: it's time they came in from the cold

We review the evolutionary ecology and genetics of telomeres in taxa that cannot elevate their body temperature to a preferred level through metabolism but do so by basking or seeking out a warm environment. This group of organisms contains all living things on earth, apart from birds and mammals. One reason for our interest in this synthetic group is the argument that high, stable body tempera...

The dyes that came in from the cold

Three groups achieve room-temperature, single-molecule detection of nonfluorescent, photon-absorbing compounds. Scientists have made steady progress in molecular-scale detection since the mid-1970s, with Tomas Hirschfeld’s pioneering efforts to observe individual fluorescently tagged proteins. Fluorescence imaging, however, is blind to many compounds. “Not all molecules are fluorescent,” says L...

The Field That Came in from the Cold

highly ordered structures, such as virus particles. More asymmetrical targets required a return to crystallography, with images captured at various angles from highly ordered 2D crystals that lock the target in a defined orientation. This electron crystallography approach allowed Henderson’s group to produce the first atomic-resolution protein structure solved by EM, of the lightresponsive prot...

The fly that came in from the cold: geographic variation of recovery time from low-temperature exposure in Drosophila subobscura

* Laboratoire Populations, Genetique, et Evolution, Centre National de la Recherche Scientifique, 91198 Gif-sur-Yvette, Cedex, France, † Laboratoire de Biometrie, Biologie Evolutive, Universite Lyon, 43 Boulevard du 11 Novembre, 69622 Villeurbanne Cedex, France, ‡ Department of Biology, Box 8795, College of William & Mary, Williamsburg, Virginia 23187–8795, USA, and § Department of Biology, Box...

Did they get what they came for? Evaluating teachers’ learning