Ectopic Fat Depots: Physiological Role And Impact On Cardiovascular Disease Continuum
نویسندگان
چکیده
Obesity is a non-infectious pandemic. The visceral distribution of adipose tissue significant factor in the development cardiovascular diseases and their complications. Along with abdominal depot omentum subcutaneous tissue, there are other ectopic depots: epicardial (EAT), perivascular (PVAT) perirenal tissue. This article presents review physiological role molecular basis PVAT EAT function healthy, as well pathological, conditions; interaction adipokines cytokines, contribution to progression diseases. discusses well-known facts controversial issues this field. Comprehensive investigation mechanisms vascular myocardial pathology obese people, along identification biomarkers for early prediction complications, would contribute targeted preventive measures choice therapeutic strategies, which consistent contemporary concept personalized medicine. We have analyzed domestic foreign literature sources eLIBRARY PubMed scientific libraries period 2001-2020.
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ژورنال
عنوان ژورنال: Russian Open Medical Journal
سال: 2022
ISSN: ['2304-3415']
DOI: https://doi.org/10.15275/rusomj.2022.0104