Early syphilis: serological treatment response to doxycycline/tetracycline versus benzathine penicillin
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چکیده
منابع مشابه
Early syphilis: serological treatment response to doxycycline/tetracycline versus benzathine penicillin.
INTRODUCTION Benzathine penicillin G is the treatment of choice for syphilis, but doxycycline and tetracycline are effective second-line treatments. The objective of this study was to assess the serological response to treatment for early syphilis with benzathine penicillin compared with doxycycline or tetracycline. METHODOLOGY We examined rapid plasma regain (RPR) serological test results of...
متن کاملSerological response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.
Background Some syphilitic patients remain in a serologically positive state after the recommended therapy. Although we often retreat patients in clinical practice, the optimal treatment protocol remains uncertain due to the paucity of data regarding serological response to retreatment and long-term outcomes. Methods We examined rapid plasma reagin serological test results of 70 serofast earl...
متن کاملSingle-dose azithromycin versus penicillin G benzathine for the treatment of early syphilis.
BACKGROUND Pilot studies suggest that a single, 2-g oral dose of azithromycin may be an alternative to a 2.4-MU intramuscular dose of penicillin G benzathine in the prevention and treatment of syphilis. We evaluated the efficacy of treatment with azithromycin in a developing country. METHODS A total of 328 subjects, 25 with primary and 303 with high-titer (a titer of at least 1:8 on a rapid p...
متن کاملComparison of Serological Response to Doxycycline versus Benzathine Penicillin G in the Treatment of Early Syphilis in HIV-Infected Patients: A Multi-Center Observational Study
BACKGROUND While doxycycline is recommended as an alternative treatment of syphilis in patients with penicillin allergy or intolerance, clinical studies to compare serological response to doxycycline versus benzathine penicillin in treatment of early syphilis among HIV-infected patients remain sparse. METHODS We retrospectively reviewed the medical records of HIV-infected patients with early ...
متن کاملRetreatment of Serofast Early Syphilis Patients With Benzathine Penicillin
Arlene C. Seña, Mark Wolff, Frieda Behets, Kathleen Van Damme, David H. Martin, Peter Leone, Linda McNeil, and Edward W. Hook Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill; EMMES Corporation, Rockville, Maryland; Department of Epidemiology, University of North Carolina at Madagascar, Antananarivo; Department of Medicine, Louisiana State Uni...
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ژورنال
عنوان ژورنال: The Journal of Infection in Developing Countries
سال: 2014
ISSN: 1972-2680
DOI: 10.3855/jidc.3013