Early postnatal stress and the serotonergic system
نویسندگان
چکیده
منابع مشابه
Early life stress affects the serotonergic system underlying emotional regulation.
Traumatic events in early life are implicated in an increased risk of psychiatric diseases, such as depression and anxiety disorders. Serotonin is thought to play a central role in stress-induced psychiatric diseases. Serotonergic systems, including neural organization and receptor function, could dramatically change with each developmental stage. Here, we reviewed the persistent influence of e...
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The dorsal raphe nucleus (DR)-serotonin (5-HT) system has been implicated in depression and is dramatically affected by swim stress, an animal model with predictive value for antidepressants. Accumulating evidence implicates the stress-related neuropeptide corticotropin-releasing factor (CRF) in the effect of swim stress on this system. This study investigated neural circuits within the DR that...
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The critical maturation time of central otolith neurons in processing spatial orientations was examined in Sprague-Dawley rats. With the use of immuno-hybridization histochemical methods, we observed c-fos expression in vestibular nuclear neurons responding to transverse movement on the horizontal plane as early as P7 and those to antero-posterior stimulation as early as P9. In the inferior oli...
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Despite abundant research studies on the physiological and biochemical nature of embryonic neurotransmitter function, little is known about the molecular genetic mechanisms involved. The expression of the main components of the serotonergic system during early Xenopus embryogenesis was investigated using RT-PCR, real time PCR and in situ hybridization. Transcripts encoding the serotonin recept...
متن کاملPostnatal development of spatial coding in the gravity sensing system
The critical maturation time of central otolith neurons in processing spatial orientations was examined in Sprague-Dawley rats. With the use of immuno-hybridization histochemical methods, we observed c-fos expression in vestibular nuclear neurons responding to transverse movement on the horizontal plane as early as P7 and those to antero-posterior stimulation as early as P9. In the inferior oli...
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ژورنال
عنوان ژورنال: Annals of General Psychiatry
سال: 2008
ISSN: 1744-859X
DOI: 10.1186/1744-859x-7-s1-s23