Early Burn Wound Excision Significantly Reduces Blood Loss
نویسندگان
چکیده
منابع مشابه
Innate response to self-antigen significantly exacerbates burn wound depth.
A major component of burn injury is caused by additional local damage from acute inflammation. Using a scald burn model in mice, we find that this part of the injury is dependent on recognition of self-antigen by specific natural IgM, leading to activation of the complement system. We propose that the depth of a burn wound is a sum of the thermal energy applied and of the degree of host inflamm...
متن کاملProspective study of burn wound excision of the hands.
To examine the role of early excision and grafting in the preservation of maximal function of hands with deep dermal burns, we prospectively evaluated 164 burned hands in consecutively admitted patients (mean age, 29 years; mean burn size, 37% of body surface). All hands with burn depths of second degree, deep second degree, or third degree above the level of the tendons and joint capsules were...
متن کاملImmediate burn wound excision restores antibody synthesis to bacterial antigen.
Although burn wound excision and grafting have been shown to improve patient survival, the effects on immune function, especially humoral immunity, are not completely understood. The purpose of this study was to investigate the effect of immediate and early wound excision on antibody synthesis and B-cell proliferation, specifically, antibody response to PGPS, a ubiquitous bacterial cell wall an...
متن کاملMinimizing blood loss in burn surgery.
BACKGROUND Significant blood loss continues to plague early tangential excision of the burn wound. Although various techniques to reduce intraoperative blood loss have been described, there is an absence of uniformity and consistency in their application. Furthermore, it is unclear whether these techniques compromise intraoperative tissue assessment and wound outcome. The purpose of this study ...
متن کاملA critical review of early burn excision and grafting
Demetrius A Miminas is a Post-graduate MSc Student in Wound Healing and Tissue Repair, Wound Healing Research Unit, Cardiff, and Trust-grade Plastic Surgeon, Russells Hall Hospital, Dudley Group of Hospitals NHS Trust, Dudley Early excision and grafting of burn wounds has largely replaced the conservative, non-excisional approach, due mainly to improvements in resuscitation and the introduction...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1990
ISSN: 0003-4932
DOI: 10.1097/00000658-199006000-00015