Early antiretroviral therapy reduces HIV DNA following perinatal HIV infection
نویسندگان
چکیده
منابع مشابه
Antiretroviral Therapy in Early HIV Infection.
Antiretroviral therapy (ART) has transformed the course of human immunodeficiency virus (HIV) infection. More than two dozen HIV drugs are now available in resource-rich environments, and newer combination regimens have ever-increasing efficacy and decreasing toxicity. As a result, life expectancy and quality of life are close to normal for HIV-infected persons with access to these medications....
متن کاملAntiretroviral Therapy in Early HIV Infection
Antiretroviral therapy (ART) has transformed the course of human immunodeficiency virus (HIV) infection. More than two dozen HIV drugs are now available in resource-rich environments, and newer combination regimens have ever-increasing efficacy and decreasing toxicity. As a result, life expectancy and quality of life are close to normal for HIV-infected persons with access to these medications....
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BACKGROUND In the Strategic Timing of Antiretroviral Treatment (START) study, immediate combination antiretroviral therapy (cART) initiation reduced cancer risk by 64%. We hypothesized that risk reduction was higher for infection-related cancer and determined by differences in CD4 cell counts and human immunodeficiency virus (HIV) RNA between the study arms. METHODS Incident malignancies in...
متن کاملAntiretroviral Therapy for HIV Infection
The HIV/AIDS is now twenty five years old and, in these 25 years, more than 60 million people have been infected by human immunodeficiency virus (HIV). As on December 2006, nearly 39.5 million people globally are living with HIV/AIDS1. During this period, lot of efforts have gone into understanding the structure of viruses, its molecular biology and the pathogenesis of disease. The information ...
متن کاملPaucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection
The latent reservoir is a major barrier to HIV eradication. Reservoir size is emerging as an important biomarker to assess the likelihood of HIV remission in the absence of antiretroviral therapy (ART) and may be reduced by earlier initiation of ART that restricts HIV spread into CD4+ T cells. Reservoir size is traditionally measured with a quantitative viral outgrowth assay (QVOA) that induces...
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ژورنال
عنوان ژورنال: AIDS
سال: 2017
ISSN: 0269-9370
DOI: 10.1097/qad.0000000000001565