EA-valve: development of a tissue-engineered elastin-based heart valve prosthesis
نویسندگان
چکیده
منابع مشابه
TexMi: development of tissue-engineered textile-reinforced mitral valve prosthesis.
Mitral valve regurgitation together with aortic stenosis is the most common valvular heart disease in Europe and North America. Mechanical and biological prostheses available for mitral valve replacement have significant limitations such as the need of a long-term anticoagulation therapy and failure by calcifications. Both types are unable to remodel, self-repair, and adapt to the changing hemo...
متن کاملFabrication and characterization of nanofibrous tricuspid valve scaffold based on polyurethane for heart valve tissue engineering
Objective(s): Tissue engineering represents a new approach to solve the current complications of the heart valve replacements by offering viable valve prosthesis with growth and remodeling capability. In this project, electrospinning and dip coating techniques were used to fabricate heart valve constructs from medical grade polyurethane (PU). Methods: Fir...
متن کاملDynamic Flexure Independently Stimulates Engineered Heart Valve Tissue Development
The independent effect of dynamic flexure on the development of tissue engineered heart valves (TEHV) was investigated. Engineered heart valve tissues were constructed by seeding ovine smooth muscle cells onto rectangular scaffold strips and incubating the resultant constructs in a dynamic flexure bioreactor or under static conditions for three weeks. Tests indicated a trend of higher effective...
متن کاملTissue engineered aortic valve
Several prostheses are available to replace degenerative diseased aortic valves with unique advantages and disadvantages. Bioprotheses show excellent hemodynamic behavior and low risk of thromboembolic complications, but are limited by tissue deterioration. Mechanical heart valves have extended durability, but permanent anticoagulation is mandatory. Tissue engineering created a new generation h...
متن کاملRoss operation with a tissue-engineered heart valve.
BACKGROUND The Ross procedure has gained increasing acceptance due to excellent hemodynamic results by replacing the diseased aortic valve with the viable autologous pulmonary valve. Consequently, the right ventricular outflow tract (RVOT) has to be reconstructed. In this report a viable heart valve was created from decellularized cryopreserved pulmonary allograft that was seeded with viable au...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.01035