منابع مشابه
P 19: The Effects of Aloe Vera Extract on Brain Edema and Blood-Brain Barrier Permeability after Traumatic Brain Injury
Introduction: Recent studies have reported that the Aloe vera (Aloe barbadensis miller) plant has anti-inflammatory and antioxidant effects. This study evaluated the neuroprotective effects of different doses of Aloe vera extract after traumatic brain injury (TBI) in male rats. Materials and Methods: In this study, 70 male rats were divided into 2 groups; each group consists of 5 of sub-g...
متن کاملBlood Brain Barrier Permeation
The large surface area and the short diffusion distance from capillaries of the blood brain barrier (BBB) to the neurons facilitate the drugs and nutrients access to the brain. Penetration of chemicals to the BBB occurs using a combination of intra and intercellular passages. Tight junctions regulate the intracellular passage of molecules according to their physicochemical properties (e.g. lipo...
متن کاملThe blood-brain barrier.
In autoimmune neurologic disorders, the blood-brain barrier (BBB) plays a central role in immunopathogenesis, since this vascular interface is an entry path for cells and effector molecules of the peripheral immune system to reach the target organ, the central nervous system (CNS). The BBB's unique anatomic structure and the tightly regulated interplay of its cellular and acellular components a...
متن کاملBlood-brain Barrier Experiment
The graphical tools (see Section 4) showed that the logarithmic transformation applied to both the response (concentration ratio) and the explanatory variable sacrifice time makes the relationship between the two variables approximately linear. In this section we will examine the relationship between the logarithm of concentration ratio (LNRATIO) and the eight explanatory variables with the fol...
متن کاملBlood-brain barrier genomics.
The blood-brain barrier (BBB) is formed by the brain microvascular endothelium, and the unique transport properties of the BBB are derived from tissue-specific gene expression within this cell. The current studies developed a gene microarray approach specific for the BBB by purifying the initial mRNA from isolated rat brain capillaries to generate tester cDNA. A polymerase chain reaction-based ...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 1961
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.3.171