Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma.
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چکیده
منابع مشابه
Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma
In steroid-resistant (SR) asthma, there is a lack of clinical responsiveness to oral prednisone. Previous studies indicate that this may be explained by the effect of the combination of interleukin 2 (IL-2) and IL-4 on glucocorticoid receptor binding affinity. By contrast, steroid-sensitive (SS) asthmatics respond well to glucocorticoids, and this is accompanied by a decrease in the numbers of ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1995
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.181.1.33