منابع مشابه
Dysplastic nevi and melanoma.
Dysplastic nevi are described as being on a continuum between common acquired nevi and melanoma because they are morphologically and biologically intermediate between these 2 entities. Since initially being reported as histologic lesions observed in melanoma-prone families, there has been considerable debate about the definition of dysplastic nevi, the histologic and clinical criteria used to d...
متن کاملMelanocytic nevi with features of Spitz nevi and Clark's/dysplastic nevi ("Spark's" nevi).
BACKGROUND Nevi with cytologic characteristics of Spitz nevus and architectural features of Clark's/dysplastic nevus are not well recognized in the literature. METHODS Twenty-seven nevi with characteristics of Spitz nevus and Clark's/dysplastic nevus are reviewed. RESULTS The patients' mean age was 33 years, and 17/27(63%) patients were female. Lesions were most frequent on the trunk and lo...
متن کاملEstrogen Receptor Beta Expression in Melanomas Versus Dysplastic Nevi
Dear Editor-in-ChiefMalignant melanoma is a tumor arising from melanocyte; this tumor rarely occurs before puberty, with higher mortality rate in males and better survival rate in female patients affected by metastatic melanoma (1, 2). These facts propose that a relationship and association may exist between estrogens and melanoma. The effects of estrogens are mediated by...
متن کاملEffect of oral isotretinoin on dysplastic nevi.
We previously reported a favorable histologic response of dysplastic nevi to topical tretinoin in three patients. To investigate the anticancer and cancer preventive effects of retinoids we have examined the effect of systemic isotretinoin on dysplastic nevi. After confirmatory baseline biopsies, eleven patients with the dysplastic nevus syndrome were treated with oral isotretinoin, 40 mg twice...
متن کاملThe frequency of histologically dysplastic nevi in 199 pediatric patients.
Many uncertainties surround the definition, frequency, and significance of dysplastic nevi in children. Consequently the management of dysplastic nevi in the pediatric population has been largely derived from the studies of adults. Biopsies are usually performed on this young age group because of lesion change or abnormal appearance. One might therefore assume that the frequency of histological...
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ژورنال
عنوان ژورنال: Cancer
سال: 1989
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19890115)63:2<386::aid-cncr2820630231>3.0.co;2-6