Dysbindin and Schizophrenia: It's Dopamine and Glutamate All Over Again
نویسندگان
چکیده
منابع مشابه
Glutamate and dopamine components in schizophrenia.
The treatment of schizophrenia for the last half century has been with dopamine (DA) D(2) receptor blockers, implicating a hyperdopamine basis for psychosis. However, a 2007 report found that the glutamate agonist LY404039 was effective in schizophrenia, suggesting a hypoglutamate state for the illness. Although phencyclidine psychosis also supports a hypoglutamate cause, assessing the basic an...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 2011
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2010.10.028