Dysbindin-1 and schizophrenia: from genetics to neuropathology
نویسندگان
چکیده
منابع مشابه
Dysbindin-1 Involvement in the Etiology of Schizophrenia
Schizophrenia is a major psychiatric disorder that afflicts about 1% of the world's population, falling into the top 10 medical disorders causing disability. Existing therapeutic strategies have had limited success on cognitive impairment and long-term disability and are burdened by side effects. Although new antipsychotic medications have been launched in the past decades, there has been a gen...
متن کاملThe neuropathology of schizophrenia
The distinguished American neurologist, Plum (1972), once called schizophrenia 'the graveyard of neuropathologists'. Certainly the topic of neuropathological change in schizophrenia has been nearly as silent as a tomb for almost three decades. Interest in the neuropathology of schizophrenia was still high in 1952 when leading neuropathologists of the world, meeting at the First International Co...
متن کاملThe neuropathology of schizophrenia.
Insofar as schizophrenia is a neuropsychiatric syndrome involving the brain, neuropathology is a promising, if not essential investigative approach. Although traditional neuropathology has yet to yield a pathognomonic lesion in schizophrenia, there have been no shortages of findings. Unfortunately, many of these findings have not only failed to be pathognomonic, but they have not been consisten...
متن کاملThe neuropathology of schizophrenia
The distinguished American neurologist, Plum (1972), once called schizophrenia 'the graveyard of neuropathologists'. Certainly the topic of neuropathological change in schizophrenia has been nearly as silent as a tomb for almost three decades. Interest in the neuropathology of schizophrenia was still high in 1952 when leading neuropathologists of the world, meeting at the First International Co...
متن کاملSchizophrenia neuropathology: tortoises and hares.
A decade ago, the neuropathology of schizophrenia was an aging tortoise being overtaken by the young hare of molecular genetics. The smart money was on positional cloning finding the schizophrenia gene(s), after which the pathobiology of the disorder would finally be revealed. The race, however, has taken a diVerent turn. The hare is no longer sure what race it is in, nor where the finishing li...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2004
ISSN: 0021-9738
DOI: 10.1172/jci200421470