Dynamin: Possible Mechanism of “Pinchase” Action
نویسندگان
چکیده
منابع مشابه
Dynamin A Molecular Motor with Pinchase Action
and Schmid (1995) provided graphic images of dynamin, under low salt conditions, assembling into rings and spirals. These structures were of similar dimensions to the " collars " about the membrane invaginations ob-in Digestive Diseases served at the nerve terminals of mutant shibire ts flies self association of dynamin was shown not to require GTP binding or hydrolysis. Thus, dynamin is the se...
متن کاملDynamin: switch or pinchase?
What is it? Dynamin is a protein that is essential for severing nascent endocytic pits from the plasma membrane to form vesicles. According to whom you speak, dynamin is either a molecular 'switch', or a pinchase-like mechanoenzyme. What is a switch and what is a mechanoenzyme? Small GTPases of the Ras superfamily are often thought of as switches that control cellular events. These enzymes, whe...
متن کاملDynamin: characteristics, mechanism of action and function.
Dynamin - a member of the GTP-ase protein family - is essential for many intracellular membrane trafficking events in multiple endocytic processes. The unique biochemical features of dynamin - especially its propensity to assemble - enable severing the nascent vesicles from the membrane. The mechanism of dynamin's action is still a subject of debate - whether it functions as a mechanochemical e...
متن کاملStudy on Antinociceptive Activity of Different Extracts of Peganum Harmala and Possible Mechanism of Action
The seeds of Peganum harmala L. ( Pgh ) (Zygophyllaceae) have been used in Moroccan traditional medicine for treatment of a various diseases and to relieve dolorous process. The major objective of this paper was to investigate the analgesic effect of ethyl acetate (EAE), butanolic (BE) and aqueous (AqE) extracts of seeds of Peganum harmala and elucided the possible underlying action mechani...
متن کاملHepatoprotective Activity of Camellia Sinensis and Its Possible Mechanism of Action
The present study appraised the hepatoprotective activity of aqueous extract of Camellia sinensis leaves and its possible mechanism of action against carbon-tetrachloride-induced liver damage. Liver damage was induced by intraperitoneal administration of equal mixture of carbon tetrachloride and olive oil (50 % v/v, 0.5 ml/kg ) in male Wistar rats (150-220g) once daily for...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1999
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(99)76917-1