Dynamic molecules

Dynamic force spectroscopy of single DNA molecules.

To explore the analytic relevance of unbinding force measurements between complementary DNA strands with an atomic force microscope, we measured the forces to mechanically separate a single DNA duplex under physiological conditions by pulling at the opposite 5'-ends as a function of the loading rate (dynamic force spectroscopy). We investigated DNA duplexes with 10, 20, and 30 base pairs with l...

Dynamic supramolecular complexation by shapeshifting organic molecules.

The synthesis of bisporphyrin bullvalene 1 enabled explorations of its supramolecular complexation with C(60), revealing a dynamic network of interconverting complexes.

Ddd: Dynamic Database for Diatomic Molecules

From molecules to dynamic biological communities

Microbial ecology is flourishing, and in the process, is making contributions to how the ecology and biology of large organisms is understood. Ongoing advances in sequencing technology and computational methods have enabled the collection and analysis of vast amounts of molecular data from diverse biological communities. While early studies focused on cataloguing microbial biodiversity in envir...

Dynamic information system for small molecules

The analysis of the biological effects of small molecules by mining lot of growing databases is an important task in the field of pharmaceutical sciences. To identify potential new similar drugs or to assess health risks from chemicals requires detailed knowledge about compounds. The pursued project is aiming at the integration of existing data resources of small molecules that are combined wit...