Durable remission of C3 glomerulonephritis with mycophenolate mofetil
نویسندگان
چکیده
منابع مشابه
Treatment of idiopathic membranoproliferative glomerulonephritis with mycophenolate mofetil and steroids.
BACKGROUND Treatment of adults with idiopathic membranoproliferative glomerulonephritis (IMPGN) is often unrewarding with approximately 60% of patients progressing to end-stage renal failure within 10 years. Although children with IMPGN may respond to steroid therapy, there is no significant benefit to treating adult IMPGN patients with immunosuppression. METHODS Outcome measures in five pati...
متن کاملMycophenolate mofetil (MMF) treatment efficacy in children with primary and secondary glomerulonephritis
INTRODUCTION The aim of our study was to analyse the efficacy and safety of mycophenolate mofetil (MMF) as part of the complex immunosuppressive therapy in children with different types of primary and secondary glomerulonephritis, who were not eligible for the standard treatment routine suggested by evidence-based guidelines. MATERIAL AND METHODS The study group comprised 85 children with pro...
متن کاملMycophenolate mofetil versus cyclophosphamide for inducing remission of ANCA vasculitis with moderate renal involvement.
OBJECTIVE We performed a single-centre non-blinded clinical trial to compare the clinical efficacies of mycophenolate mofetil (MMF) and intermittent cyclophosphamide (CTX) pulse therapy as induction treatments in patients with antineutrophil cytoplasmic antibody (ANCA) vasculitis (AAV) and moderate renal involvement. METHODS Patients with active AAV and serum creatinine <500 micromol/L receiv...
متن کاملTherapeutic monitoring of mycophenolate mofetil.
M ycophenolate mofetil (MMF) has become the single most used immunosuppressant in solid-organ transplantation. Despite a well-documented relationship and efficacy (in terms of acute rejection prophylaxis) and exposure to mycophenolic acids (MPA) as measured by area under the curve (AUC), excellent results have been achieved using a fixed-dosage regimen. In the past several years, there has been...
متن کاملSingle application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis.
IgA nephropathy, one of the most frequent forms of glomerulonephritis, characterized by mesangial hypercellularity and glomerular extracellular matrix (ECM) expansion, often leads to end-stage renal disease over a prolonged period. We investigated whether antiproliferative treatment in a single low dose specifically targeted to the glomerular mesangium by immunoliposomes (ILs) results in an ame...
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ژورنال
عنوان ژورنال: Nephrology
سال: 2017
ISSN: 1320-5358
DOI: 10.1111/nep.12939