Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
نویسندگان
چکیده
منابع مشابه
Liposomal drug delivery in multimodal cancer therapy
Encapsulating cytostatics into lipid vesicles, i.e. liposomes, improves tumour drug accumulation and reduce adverse effects. Liposomal doxorubicin (DXR) has been used in the treatment of a variety of cancers and may also be suitable for combining with other treatment modalities. By modulating liposomal membranes, liposomes can be made ultrasound (US) sensitive releasing encapsulated drug in tum...
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A dual stimuli-responsive multi-drug delivery system was developed for "cancer cocktail therapy". Upon UV irradiation, microcapsules could rapidly release the small-molecule drugs, and thereafter the macromolecular drugs would be released in the presence of MMP in the tumor cells. This system will find great potential as a novel chemotherapeutic combination for cancer treatment.
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ژورنال
عنوان ژورنال: ACS Pharmacology & Translational Science
سال: 2021
ISSN: 2575-9108,2575-9108
DOI: 10.1021/acsptsci.1c00066