Dual Roles of the Mammalian GARP Complex in Tethering and SNARE Complex Assembly at the trans -Golgi Network
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چکیده
منابع مشابه
Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network.
Tethering factors and SNAREs control the last two steps of vesicular trafficking: the initial interaction and the fusion, respectively, of transport vesicles with target membranes. The Golgi-associated retrograde protein (GARP) complex regulates retrograde transport from endosomes to the trans-Golgi network (TGN). Although GARP has been proposed to function as a tethering factor at the TGN, dir...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2009
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.00495-09