Drug Resistance of Tubercle Bacilli

Some Fundamental Investigations on the Resistance of Tubercle Bacilli.

The detection of streptomycin resistance in tubercle bacilli.

It has been shown (Dye, Lynch, and Brees, 1953; Medical Research Council, 1953a and b; Pitts, Tempel, Miller, Sands, Fitzpatrick, and Weiser, 1953) that the treatment of tuberculosis with two drugs simultaneously markedly reduces the incidence of bacterial resistance provided that the organisms are fully sensitive to both drugs. If, however, the organisms are resistant to one of the drugs, resi...

Prevalence of Drug Resistance in Nonfermenter Gram-Negative Bacilli

  Background and Objectives: Non-fementer gram-negative bacilli (NFGB) are ubiquitous pathogen that has emerged as a major cause of health care associated infections. The aim of this study was to determine the prevalence and antimicrobial susceptibility of   NFGB in an Iranian hospital. Materials and Methods: FromJuly 2005 to November 2006 a total of 257 strains of NFGB including 109 (42.41%)...

DIFFERENTIATION OF LEPROSY AND TUBERCLE BACILLI. 219 On the Differentiation of Leprosy and Tubercle Bacilli

On the nucleoproteins of avian tubercle bacilli.

The nucleic acids of tubercle bacilli have formed the subject of several studies, among which may be mentioned those by Ruppel (l), Levene (2), and Johnson and his associates (3-5). The work of Mensel and Heidelberger (6) on the fractionation of the proteins of the tubercle bacillus revealed the presence of several protein fractions, rich in phosphorus and in purines, which appeared to be nucle...