Drug Interactions between Antimicrobial and Immunosuppressive Agents in Solid Organ Transplant Recipients

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Antimicrobial and immunosuppressive drug interactions in solid organ transplant recipients.

Infections are frequent and can be severe in recipients of solid organ transplantation. Prevention and treatment are priority objectives of multidisciplinary transplant teams. Interactions between antimicrobials (indicated for prevention and therapy) and immunosuppressants (for preventing rejection) make treatment more complex than in the general population. Co-administration of immunosuppressa...

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Parasitic diseases are rare infections after a solid organ transplant (SOT). Toxoplasmosis, Trypanosoma cruzi, and visceral leishmanias are the 3 main opportunistic protozoal infections that have the potential to be lethal if not diagnosed early and treated appropriately after SOT. Strongyloides stercoralis is the one helminthic disease that is life-threatening after transplant. This review add...

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Infections in Pediatric Solid Organ Transplant Recipients.

Infectious complications are an important cause of morbidity and mortality in children undergoing solid organ transplantation. Knowledge gained over the last 30 years provides a growing understanding of these infections. This review identifies risk factors for and timing of infections describes the common infectious syndromes and pathogens seen in children undergoing solid organ transplantation...

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Viral hepatitis in solid organ transplant recipients.

Hepatotropic viral infections are frequent in allograft recipients and may be caused by a number of different viruses. Of these, the most important infectious agents are hepatitis B virus (HBV) and hepatitis C virus (HCV), which can cause both acute and chronic hepatitis. In addition, Hepatitis E virus (HEV), thought previously to only cause acute hepatitis in the developing world, is emerging ...

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ژورنال

عنوان ژورنال: Indian Journal of Critical Care Medicine

سال: 2021

ISSN: 0972-5229,1998-359X

DOI: 10.5005/jp-journals-10071-23439