Drug interaction between St John's Wort and quazepam

Drug interactions with St John's wort.

discussed the potential for St. John’s wort (SJW) to cause drug interactions. At that time, SJW had been identified as an inducer of cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp). We discussed the interactions with alprazolam, oral contraceptives, and several antiretroviral drugs. In each case, SJW was shown to increase the metabolism of the object drug resulting in a reduction in effi...

Drug interactions with St John's wort : mechanisms and clinical implications.

The purpose of this paper is to review preclinical and clinical evidence relating to drug interactions with preparations of the medicinal herb St John's wort (Hypericum perforatum). A systematic literature search was carried out in three electronic databases up to June 2004. Information about case reports classified as St John's wort drug interactions was retrieved from the WHO Collaborating Ce...

St. John's wort.

St John's wort and depression.

St. John's wort is a plant with yellow flowers that has been used for centuries for health purposes, such as for depression and anxiety. This fact sheet answers some frequently asked questions about St. John's wort and depression, and summarizes what the science says about its effectiveness and the research being done. • Studies suggest that St. John's wort is of minimal benefit in treating maj...

St. John's Wort and Depression

St. John's Wort scientifically known as Hypericum Perforatum, an herbal remedy generally used to treat depression, is making a rise throughout Europe and the United States. St. John's Wort is a perennial plant that produces abundant yellow flowers and grows naturally throughout much of the world, including specifically in northern California, southern Oregon, and Colorado. It usually flowers on...