Drug Induced Kidney Disease

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Phenotype standardization for drug-induced kidney disease.

Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders. We convened a panel of international, adult and pediatric, nephrologists and pharmacists to develop standardized phenotypes for drug-induced kidney disease as part of the phenotype standardization project initiated by the Internation...

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Drug-induced kidney diseases.

Drug-induced kidney disease constitutes an important cause of acute renal failure and chronic kidney disease in present day clinical practice. Different classes of drugs, by virtue of immunological mechanisms or direct toxicity initiate certain stereotyped renal responses. For most patients suffering from drug-induced nephropathy common risk factors which precipitate the adverse effects include...

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Drug-induced kidney disease--pathology and current concepts.

The kidneys can be damaged by a large number of therapeutic agents. The aim of this article is to discuss the pathological features of drug-induced renal disease as diagnosed by kidney biopsy. The literature is reviewed and cases seen by the authors that have a known drug association are analysed. Mechanisms of injury are varied and all renal structures may be affected. The tubulointerstitial c...

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7. Drug-Induced Kidney Injury

Acute kidney injury is an independent risk factor for patient mortality, even with small decrements in kidney function. In addition, it increases length of stay in the hospital and increases cost of treatment. Renal injury is often multifactorial, with drugs being only one of the factors in its pathogenesis. Hence, it is often difficult to estimate involvement of drugs as a cause of acute kidne...

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ژورنال

عنوان ژورنال: Open Access Journal of Toxicology

سال: 2017

ISSN: 2474-7599

DOI: 10.19080/oajt.2017.02.555576