Drug discovery of CLK1 inhibitors and their activity evaluation as anti‐influenza viral agents (654.11)
نویسندگان
چکیده
منابع مشابه
Drug Discovery of Host CLK1 Inhibitors for Influenza Treatment.
The rapid evolution of influenza virus makes antiviral drugs less effective, which is considered to be a major bottleneck in antiviral therapy. The key proteins in the host cells, which are related with the replication cycle of influenza virus, are regarded as potential drug targets due to their distinct advantage of lack of evolution and drug resistance. Cdc2-like kinase 1 (CLK1) in the host c...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2014
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.28.1_supplement.654.11