Drug delivery in ocular diseases: Barriers and strategies
نویسندگان
چکیده
منابع مشابه
Ocular Drug Delivery Barriers—Role of Nanocarriers in the Treatment of Anterior Segment Ocular Diseases
Ocular drug delivery is challenging due to the presence of anatomical and physiological barriers. These barriers can affect drug entry into the eye following multiple routes of administration (e.g., topical, systemic, and injectable). Topical administration in the form of eye drops is preferred for treating anterior segment diseases, as it is convenient and provides local delivery of drugs. Maj...
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INTRODUCTION Ocular targeted therapy has enormously been advanced by implementation of new methods of drug delivery and targeting using implantable drug delivery systems (DDSs) or devices (DDDs), stimuli-responsive advanced biomaterials, multimodal nanomedicines, cell therapy modalities and medical bioMEMs. These technologies tackle several ocular diseases such as inflammation-based diseases (e...
متن کاملOcular Drug Delivery
Traditionally, medication is delivered to the eye by three main mechanisms: Topical ocular administration, systemic administration, and intraocular or periocular injection. Each of these methods has significant disadvantages. Topical ocular solutions or ointments have less than a 1% penetration, have rapid dilution and tear washout, and rely substantially on owner compliance to administer the m...
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Effective diagnostic and therapeutic intervention of genetic diseases have been particularly pending on technological development. It was not until the last two decades of the past century that molecular biology and recombinant DNA have provided diagnostic and therapeutic tools for these diseases. Since then, our understanding of the biological processes underscoring genetic conditions and the ...
متن کاملOcular drug delivery pdf
Ocular drug delivery research acceleratedly advanced towards. Ocular drug delivery necessitates and helps drug delivery scientists to. Urgent need to develop ocular drug delivery systems which provide controlled. Pdflucentis-prescribing.pdf accessed on 18 October 2010. Delivery system, therefore, desires an integrated knowledge of the drug molecule and the restrictions offered by the ocular rou...
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ژورنال
عنوان ژورنال: World Journal of Pharmacology
سال: 2013
ISSN: 2220-3192
DOI: 10.5497/wjp.v2.i4.78