منابع مشابه
Automatic Detection of Spironolactone - Related Adverse Drug Events
Due to increasing reports of spironolactone associated life-threatening hyperkalemia, we implemented a rule in our automated event detection system to monitor serum potassium results in patients receiving spironolactone. In 2004, 419 (10.49%) of 3995 admissions at 3 BJC HealthCare hospitals were identified as having hyperkalemia while on spironolactone. For a 9-month period in one facility, 33 ...
متن کاملSpironolactone and Chf
• Objective: To assess the impact of interventions to increase the use of spironolactone in patients with congestive heart failure (CHF) due to ventricular systolic dysfunction. • Methods: Charts of patients admitted to the medicine department of a single hospital with a primary diagnosis of class IV CHF and left ventricular ejection fraction of 40% or less were randomly selected and reviewed. ...
متن کاملSpironolactone and diabetic ketoacidosis.
Introduction Spironolactone is a specific competitive antagonist of aldosterone, the most potent endogenous mineralocorticoid, which modifies renal electrolyte handling and is therefore commonly used as a diuretic in conditions associated with secondary hyperaldosteronism. In renal insufficiency, aldosterone antagonists may induce significant hyperkalaemia even if administered concurrently with...
متن کاملSpironolactone-Induced Unilateral Gynecomastia
Gynecomastia is benign enlargement of male breast, drug-induced gynecomastia accounts for about 25%. We are reporting a case of spironolactone-induced unilateral gynecomastia. A 52-year-old male patient receiving multiple antihypertensives including hydrochlorothiazide presented with muscle weakness and easy fatigability. Investigations revealed hypokalemia; he was advised to stop hydrochloroth...
متن کاملSpironolactone-associated hyponatremic coma.
Dr. Michael M. Hirschl, Department of Emergency Medicine, New General Hospital, Währinger Gürtel 18-20, A-1090 Vienna (Austria) Admission Dear Sir, Hyponatremia is the most common electrolyte abnormality observed in a general hospitalized population, seen in about 2% of patients [1]. Common causes of hyponatremia are the syndrome of inappropriate secretion of antidiuretic hormone, water intoxic...
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ژورنال
عنوان ژورنال: Journal of Prescribing Practice
سال: 2019
ISSN: 2631-8385,2631-8393
DOI: 10.12968/jprp.2019.1.12.579